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DeCS
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Descriptor English:
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AlkB Enzymes
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Descriptor Spanish:
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Enzimas AlkB
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Descriptor Portuguese:
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Enzimas AlkB
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Synonyms English:
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AlkB Homologs
Alkylated DNA Repair Protein AlkB Homologs
Alkylation Repair Homolog Proteins
Alkylation Repair Homologs
Enzymes, AlkB
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Tree Number:
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D08.811.074.062
D08.811.682.690.416.139
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Definition English:
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A family of alpha- KETOGLUTARIC ACID and Fe(II)-dependent dioxygenases that are homologous to AlkB, an enzyme that repairs alkylated nucleic acids in E. coli. The mammalian homologs have diverse substrate specificities and functions that include DNA REPAIR, generating unique wobble modifications in URIDINE tRNA, demethylation of nucleotides in DNA and RNA, and demethylation of LYSINE residues on certain proteins, including ACTIN and histones (HISTONE CODE). |
History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56458
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Unique Identifier:
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D000071496
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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